DETAILED NOTES ON B220

lumacaftor/ivacaftor will reduce the level or impact of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of abemaciclib with strong CYP3A4 inducers decreases plasma focus of abemaciclib and its metabolites.Metabolism Datopotamab deruxtecan-dlnk undergoes intracellular cleavage by